Christina Applegate, who is battling multiple sclerosis, has revealed a heartbreaking comment her 14-year-old daughter Sadie made about her condition.

The 53-year-old actress was diagnosed with the degenerative illness in 2021 after suffering what she described as ‘six or seven years of symptoms.’

Now she has shared she and Sadie ‘got into a big thing the other day, and – sorry Sadie, but it has to be said – she says: “I miss you who were before you got sick.”‘

She made the disclosure while discussing her health problems during an appearance on Kelly Ripa‘s podcast Let’s Talk Off-Camera.

‘And that just like – it’s like knife to heart because I miss who I was before I got sick too, very much so. Everyday of my life, it’s such a loss,’ Christina confessed.

The Married… with Children star said that she gets ‘up in the morning’ for Sadie’s sake, adding: ‘She’s the reason I’m still here and trying.’

Christina Applegate, who is battling multiple sclerosis, has revealed a heartbreaking comment her daughter Sadie, 14, made about her condition; mother and daughter pictured last year

She has been candid about her health struggles on her podcast MeSsy, which she co-hosts with The Sopranos actress Jamie-Lynn Sigler, who has the same condition.

Jamie-Lynn and Christina were making a joint appearance on Kelly Ripa’s podcast when the subject of Sadie’s shattering comment arose.

Christina revealed last year that Sadie was diagnosed with a neurological condition called postural orthostatic tachycardia syndrome (POTS).

POTS causes the patient’s heart rate to quicken when sitting or standing up, in a phenomenon heightened by hot weather.

‘When I stand up, I get really, really dizzy and my legs get really weak, and I feel like I’m going to pass out,’ Sadie explained on her mother’s podcast.

Christina shares her daughter with her second and current husband Martyn LeNoble, the Dutch bassist for the rock band Porno For Pyros.

She announced last year that she is writing a memoir, and it has since emerged the book is scheduled for publication by Little, Brown and Company next March.

Before she developed multiple sclerosis, Christina’s health problems included a 2008 diagnosis with breast cancer, for which she underwent a double mastectomy, and a struggle with anorexia during the early years of her stardom.

She made the disclosure while discussing her health problems during an appearance on Kelly Ripa’s podcast Let’s Talk Off-Camera; pictured January 2023

Last year, amid her harrowing experience with multiple sclerosis, Christina revealed the ‘things I want to do with the days I have left in life.’

Writing on X, formerly Twitter, she shared: ‘I want to work with Shirley MacLaine And do shots with Cher! And yes my days are so big. Just saying.’

Christina at one point raised concerns among her fans by remarking on her podcast: ‘I don’t enjoy living. I don’t enjoy it. I don’t enjoy things anymore.’

As her fans expressed their fears for her on social media, she issued a clarification saying that she finds it ‘healing’ to be frank about her emotional turmoil.

She acknowledged that she harbors ‘dark thoughts’ but argued: ”By making such a big deal about it you’re making other people think: “Oh, s***, I can’t talk about this.” And that is not okay with me. I think it’s important to be able to say these things.’