Eric Dane is speaking out for the first time since going public with his ALS diagnosis.

The Grey’s Anatomy alum, 52, revealed in April that he’s battling amyotrophic lateral sclerosis, a rare and incurable neurological condition that progressively weakens muscles and affects physical function.

The heartbreaking health news came shortly after Dane and his estranged wife, actress Rebecca Gayheart, 53, decided to call off their divorce after seven years apart. 

The pair share two daughters — Billie, 15, and Georgia, 13.

On Thursday, Dane appeared in a teaser for an upcoming Good Morning America interview with Diane Sawyer, offering a deeply personal glimpse into how he’s coping with the diagnosis.

‘I wake up every day and I’m immediately reminded that this is happening,’ he told Sawyer. ‘It’s not a dream.’

Eric Dane is speaking out for the first time since going public with his ALS diagnosis

On Thursday, Dane appeared in a teaser for an upcoming Good Morning America interview with Diane Sawyer, offering a deeply personal glimpse into how he’s coping with the diagnosis

In the emotional 30-second preview, the Euphoria star is seen holding hands with Sawyer as they reflect on his journey.

At one point, Dane is seen walking alongside Sawyer, their conversation taking a deeply personal turn.

The actor becomes visibly emotional, wiping away tears as he opens up, declaring, ‘I don’t think this is the end of my story. I don’t feel like this is the end of me.’

Two months ago, Dane released a statement about his condition, expressing gratitude for the strong support system he has in place.

‘I am grateful to have my loving family by my side as we navigate this next chapter,’ he said.

‘I feel fortunate that I am able to continue working and am looking forward to returning to set of Euphoria next week.

‘I kindly ask that you give my family and I privacy during this time.’

It’s still unclear whether Dane has finished filming for the third season of the hit HBO series, which also stars Zendaya and Sydney Sweeney.

‘I wake up every day and I’m immediately reminded that this is happening,’ he told Sawyer. ‘It’s not a dream’

At one point, Eric Dane is seen walking alongside Diane Sawyer under the sun, their conversation taking a deeply personal turn

The actor becomes visibly emotional, wiping away tears as he opens up, declaring, ‘I don’t think this is the end of my story. I don’t feel like this is the end of me’

The heartbreaking health news came shortly after Dane and his estranged wife, actress Rebecca Gayheart , 53, decided to call off their divorce after seven years apart; The pair share two daughters — Billie, 15, and Georgia, 13;( seen with their girls in 2016)

Gayheart seen with her and Dane’s two daughters Billie Beatrice Dane, 15, and Georgia Geraldine Dane, 13

Eric announced his diagnosis one day after Rebecca said they were ‘best of friends,’ adding: ‘We are really close. We are great co-parents.’

She explained that she and Eric ‘really figured out the formula to staying a family and I think our kids are benefiting greatly from it and we are as well,’ via E! News.

‘I think it’s important to not look at a relationship that ends as a failure. It’s just a season. It wasn’t a failure. It was a huge success. We were married for, I mean, we are still married, but together for 15 years and we had two beautiful kids so I think that’s a successful relationship, and that’s how we look at it.’

In March. it emerged that Eric and Rebecca had performed a stunning U-turn and called off their divorce, seven years into the process.

Rebecca filed to dissolve their marriage of 14 years in 2018, but the pair stayed notably amicable as they raised their daughters.

Rebecca and Eric were given ‘final notice’ in January that their divorce might be tossed if they neglected to advance the process, according to In Touch Weekly.

Eric was spotted that month strolling arm in arm with actress Priya Jain, 27, igniting speculation he had moved on to a new romance.

Priya and Eric first set off a round of relationship rumors this past November when they were glimpsed out on a sushi date in West Hollywood.

It’s still unclear whether Dane has finished filming for the third season of the hit HBO series, which also stars Zendaya and Sydney Sweeney

Rebecca and Eric tied the knot in 2004, two years before he landed his fan favorite role as Dr. Mark Sloan aka ‘McSteamy’ on Grey’s Anatomy (pictured)

Eric is pictured in a group shot for Grey’s Anatomy with his co-stars (from left) Ellen Pompeo, Patrick Dempsey and Sandra Oh

Meanwhile, Rebecca was seen in February attending Chanel’s pre-Oscars party in Beverly Hills with restaurant tycoon Peter Morton, 77, a co-founder of Hard Rock Café and the son of the namesake of Morton’s Steakhouse.

Rebecca and Eric tied the knot in 2004, two years before he landed his fan favorite role as Dr. Mark Sloan aka ‘McSteamy’ on Grey’s Anatomy.

ALS, widely known in the U.S. as Lou Gehrig’s disease following the legendary baseball player’s death in 1941 at just 37, has claimed the lives of several high-profile figures in recent years.

Sandra Bullock’s longtime partner, Bryan Randall, passed away in 2023 after quietly battling the disease for three years.

SpongeBob SquarePants creator Stephen Hillenburg also succumbed to ALS in 2018, just a year after revealing his diagnosis.

Famed physicist Stephen Hawking, one of the most well-known individuals to live with ALS, defied the odds by surviving more than 50 years with the condition before his death at age 76 in 2018.

In February, music icon Roberta Flack—known for classics like Killing Me Softly With His Song—died at 88 after revealing in 2022 that she had been diagnosed with ALS.